Usage And Safety
Dosage
ADULTS: Dosage: 50-150mg daily in two or three divided doses. CHILDREN: 6mnth-18yr, 1.5-2.5mg/kg ( max 75mg ) twice daily; total daily dose may alternatively be given in 3 divided doses. Always consult your doctor or Pharmacist for dose adjustment.
Side Effects
Transient epigastric pain, GI disturbances, headache, oedema. Rarely blood dyshaematopoiesis, peptic ulcers, abnormalities of liver kidney function, skin reactions, pain at injection site.
Drug Interactions
Anticoagulants, antidiabetics, diuretics, methotraxate, lithium, digoxin, cyclosporin, tacrolimus, other NSAIDS, salicylates, corticosteroids, quinolones, mifepristone, antihypertensives, antiplatelets.
Indication
For relief of the signs and symptoms of Osteoarthritis, Rheumatoid Arthritis. For acute or long-term use in the relief of signs and symptoms of Ankylosing Spondylitis . Also indicated for controlling pain and inflammation in Acute Gout and minor surgery. It is also indicated for Chronic Juvenile Arthritis .
When not to Use
Severe hepatic or renal impairment. Ischaemic heart diseases, cerebrovascular diseases, peripheral arteial disease, CHF.
Warnings
Warning 1
History of gastro-intestinal disease. Renal or hepatic or cardiac insufficiency and haematological abnormalities.
Warning 2
On long term therapy monitor liver function , blood counts.
Warning 3
Discontinue medication and inform prescriber if there is constant stomach pain, cramps , blood in stool.
