Usage And Safety
Dosage
Adults: The recommended initial dose is 10 mg. The dose may be increased to 20 mg after one to two weeks depending on the clinical effect. Doses higher than 20 mg do not provide a significant increase in effect and can cause increase in common adverse events. In patients who previously have tolerated oral 2-agonists well, the recommended initial dose is 20 mg. OR As directed by your physician.
Side Effects
Headache Palpitations, tremor, tonic muscles, cramps, urticaria and exanthema Rare (< 0.1%) Hypokalaemia, Nausea, restlessness, atrial fibrillation, supraventricular tachycardia and extrasystoles.
Drug Interactions
Suxamethonium (succinylcholine) and other muscle relaxants, beta-stimulants, xanthine derivatives and diuretics.
Indication
It is used in Bronchial asthma, Chronic bronchitis, emphysema and other lung diseases, where bronchospasm is a complicating factor.
When not to Use
Contraindicated in pregnancy Hypersensitive and seriously impaired liver functions.
Warnings
Warning 1
As terbutaline is excreted mainly via the kidneys, the initial dose should be halved in patients with an impaired renal function (GFR 50 ml/min). In patients with liver cirrhosis, and probably in patients with other causes of severely impaired liver function, the daily dose must be individualized.
Warning 2
Particular caution is recommended in acute severe asthma as the associated risk may be augmented by hypoxia .
Warning 3
Transient hypoglycaemia has been reported in newborn pre-term infants after maternal .
