₨35.30
Yes
Linagliptin
Diabetes
Linagliptin is an inhibitor of the enzyme DPP-4 (dipeptidyl peptidase 4) an enzyme which is involved in the inactivation of the incretin hormones GLP-1 and GIP (glucagon-like peptide1, glucose-dependent insulinotropic polypeptide). These hormones are rapidly degraded by the enzyme DPP-4. Both incretin hormones are involved in the physiological regulation of glucose homeostasis. Incretins are secreted at a low basal level throughout the day and levels rise immediately after meal intake. GLP-1 and GIP increase insulin biosynthesis and secretion from pancreatic beta cells in the presence of normal and elevated blood glucose levels. Furthermore GLP-1 also reduces glucagon secretion from pancreatic alpha cells, resulting in a reduction in hepatic glucose output.
Adults : 5mg daily. In combination therapy consider lower dose of sulphonylurea or insulin. Children : Not Recommended. OR As directed by your physician.
• Swelling of the nose or throat (nasopharyngitis) • mouth ulceration • cough • painful, swollen joints • back pain • headache • aching muscles, muscle tenderness or weakness not caused by exercise • symptoms of urinary tract infection (such as an urge to urinate frequently and in small amounts, painful burning when passing urine) • sweating • weakness • hunger • dizziness • trembling • headache • flushing or paleness • numbness • a fast, pounding heartbeat.
Carbamazepine, phenobarbital or phenytoin , rifampicin
It is used for ‘type 2 diabetes’ in adults, if the disease cannot be adequately controlled with one oral anti-diabetic medicine (metformin or sulphonylureas) or diet and exercise alone. It may be used together with other anti-diabetic medicines e.g. metformin, sulphonylureas (e.g. glimepiride, glipizide), empagliflozin, or insulin.
Do not take if you are allergic to linagliptin or any of the other ingredients of this medicine .
Linagliptin should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
Sulphonylureas and insulin are known to cause hypoglycaemia. Therefore, caution is advised when linagliptin is used in combination with a sulphonylurea and/or insulin. A dose reduction of the sulphonylurea or insulin may be considered .
If you have symptoms of acute pancreatitis, like persistent, severe stomach ache (abdominal pain), you should consult your doctor .
Diabetic skin lesions are a common complication of diabetes. You are advised to follow the recommendations for skin and foot care that you are given by your doctor or nurse.
Always consult your physician before using any medicine.
Store this medicine at room temperature, away from direct light and heat.