Dosage
For patients weighing 50kg (110lb) or more : Give Ferric Carboxymaltose in two doses separated by at least 7 days. Give each dose as 750mg for a total cumulative dose not to exceed 1500 mg of iron per course. For patients weighing less than 50kg (110 lb) : Give Ferric Carboxymaltose in two doses separated by at least 7 days. Give each dose as 15mg/kg body weight for a total cumulative dose not to exceed 1500mg of iron per course. Administer Ferric Carboxymaltose intravenously, either as an undiluted slow intravenous push or by infusion OR As directed by your physician .
Side Effects
Common: Nausea, dizziness, gastrointestinal disturbances, headache, injection site reactions, rash, hypophosphatemia, hypertension. Uncommon: Anaphylaxis, arthralgia, back pain, chest pain, fatigue, flushing, hypotension, malaise, tachycardia, myalgia, paraesthesia, dysgeusia, peripheral oedema, chills, pruritus, pyrexia, rigors, urticaria. Rare: Dyspnoea, loss of consciousness, anxiety, phlebitis, syncope, flatulence, pallor.
Drug Interactions
The absorption of oral iron is reduced when administered concomitantly with parenteral iron preparations. Therefore, if required, oral iron therapy should not be started for at least 5 days after the last injection of Ferric Carboxymaltose.
When not to Use
Known hypersensitivity to the active substance, or any of its excipients or serious hypersensitivity to other parenteral iron products, anemia not attributed to iron deficiency, e.g. other microcytic anemia and evidence of iron overload or disturbances in the utilisation of iron.
