Dosage
The recommended starting dose (Ertugliflozin + Sitagliptin) is 5mg Ertugliflozin + 100mg Sitagliptin once daily, taken in the morning, with or without food. In patients tolerating (Ertugliflozin + Sitagliptin), the dose may be increased to a maximum recommended dose of 15mg Ertugliflozin + 100mg Sitagliptin, once daily or as prescribed by your physician.
Side Effects
Pancreatitis, hypotension, ketoacidosis, acute kidney injury, impairment in renal function, urosepsis, pyelonephritis, lower limb amputation, heart failure, hypoglycemia with concomitant use with insulin and insulin secretagogues, necrotizing fasciitis of the perineum (fournier’s gangrene), genital mycotic infections, hypersensitivity reactions, increases in low-density lipoprotein, severe and disabling arthralgia, bullous pemphigoid, upper respiratory tract infection, nasopharyngitis, urinary tract infections, vaginal pruritus, increased urination, back pain, weight decreased and headache.
When not to Use
Known hypersensitivity to Ertugliflozin, Sitagliptin and to any of the excipient of the product. – Severe renal impairment, end-stage renal disease (ESRD) or on dialysis.
