Usage And Safety
Dosage
Amoxicllin , Clavulanic Acid
Side Effects
Mucocutaneous candidiasis , Reversible leucopenia (including neutropenia) and thrombocytopenia , Angioneurotic oedema, anaphylaxis, serum sickness-like syndrome, hypersensitivity vasculitis , Dizziness, headache , Diarrhoea , Nausea, vomiting , Indigestion .
Drug Interactions
Mycophenolate mofetil , Probenecid , Oral contraceptives , acenocoumarol or warfarin .
Indication
It is an antibiotic agent with a notably broad spectrum of activity against the commonly occurring bacterial pathogens .
When not to Use
It is contraindicated in patients with a history of hypersensitivity to betalactams, e.g. penicillins and cephalosporins.
Warnings
Warning 1
Serious and occasionally fatal hypersensitivity reactions (including anaphylactoid and severe cutaneous adverse reactions) have been reported in patients on penicillin therapy. These reactions are more likely to occur in individuals with a history of penicillin hypersensitivity.
Warning 2
Prolonged use may also occasionally result in overgrowth of non-susceptible organisms.
Warning 3
In patients with renal impairment, Co-Amoxiclav dosage should be adjusted as recommended.
