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Rezam Tablets 15mg

₨488.00

Quantity:
SKU: MD-6812 Categories: , , ,

Description

Requires Prescription (YES/NO)

Yes

Generics

Mirtazapine

Used For

Depression

How it works

Mirtazapine is a centrally active presynaptic a2 -antagonist, which increases central noradrenergic and serotonergic neurotransmission. The enhancement of serotonergic neurotransmission is specifically mediated via 5-HT1 receptors, because 5-HT2 and 5-HT3 receptors are blocked by Mirtazapine. The histamine H1-antagonistic activity of Mirtazapine is associated with its sedative properties.

Usage And Safety

Dosage

Adults : Initial starting dose is 15mg once daily at night. Titrate according to response , usually 15-45mg as a single dose at night or in two equally divided doses morning and night. Withdraw gradually when symptoms free 4-6 months. Children : Not recommended. OR As directed by your physician .

Side Effects

Bone marrow depression (granulocytope-nia, agranulo-cytosis, aplastic anaemia, thrombo-cytopenia) , Eosinophilia , Weight increased , Increase in appetite Abnormal dreams , Confusion , Anxiety , Insomnia , Nightmares , Mania , Agitation , Hallucinations , Psychomotor restlessness (incl. akathisia, hyperkinesia) , Aggression , Suicidal ideation , Suicidal behaviour , Somnolence Sedation , Headache , Lethargy , Dizziness , Tremor , Paraesthesia , Restless legs, Syncope, Myoclonus , Convulsions (insults) , Serotonin syndrome , Oral paresthaesia , Dysarthria.

Drug Interactions

MAO inhibitors , SSRIs , benzodiazepines and other sedatives (notably most antipsychotics, histamine H1 antagonists, opioids , alcohol.

Indication

Treatment of episodes of major depression in adults.

When not to Use

• Hypersensitivity to the active substance • Concomitant use of Mirtazapine with monoamine oxidase (MAO) inhibitors.

Precautions

Precaution

Mirtazapine should not be used in the treatment of children and adolescents under the age of 18 years. Suicide-related behaviors (suicide attempt and suicidal thoughts), and hostility (predominantly aggression, oppositional behavior and anger) may occur among children and adolescents treated with antidepressants.

Warnings

Warning 1

The patient should be carefully monitored for the appearance of suicidal symptoms.

Warning 2

Bone marrow depression, usually presenting as granulocytopenia or agranulocytosis, may occur rarely during treatment with Mirtazapine.

Warning 3

Treatment should be discontinued if jaundice occurs.

Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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