GTN (Glyceryl Trinitrate) 0.2% cream is a topical ointment used to treat pain from conditions like chronic anal fissures and post-hemorrhoidectomy, by relaxing the anal sphincter muscle to improve blood flow. It is applied to the anal area to help heal tears and ease pain caused by muscle spasm. While effective, it can cause side effects, most commonly headaches.
How it works
- The active ingredient, glyceryl trinitrate, acts as a vasodilator, relaxing the smooth muscle of the internal anal sphincter.
- This relaxation increases blood flow to the area, which helps the fissure heal and provides pain relief.
- It is used for chronic anal fissures and can also help with pain and healing time after hemorrhoidectomy surgery.
How to use
- Apply a small amount of the ointment (about the size of a pea) to the affected area, typically twice a day, or as directed by a doctor.
- Some doctors may advise applying it 5-10 minutes before a bowel movement to help with pain during that time.
- A doctor will provide a prescription for the medication, which is available at a pharmacy.
Side effects
- The most common side effect is a headache, which may be severe, especially with initial use.
- Other potential side effects include skin irritation or allergic reactions.
- If irritation persists or if you experience severe side effects, discontinue use and consult your doctor.
Important considerations
- GTN 0.2% cream is intended for external use only and should be kept out of reach of children.
- Avoid contact with eyes and rinse with water if contact occurs.
- Although effective, some studies show other treatments like lateral sphincterotomy may have a higher healing rate for anal fissures.
- It’s essential to follow your doctor’s guidance for proper use and to discuss any concerns or side effects.
